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Table 4 Assessment of blood chemistry changes denoting lipids, glucose, muscle and hepatorenal function concordant to supplementation

From: Acute and chronic safety and efficacy of dose dependent creatine nitrate supplementation and exercise performance

   

Treatment

 
   

PLA

CrM

CrN-Low

CrN-High

Chi-Square

 

Cholesterol

No Change

0

0

0

0

0.33

  

Normal Base; Exceed Day 7

10

8

12

13

 
  

Normal Base; Exceed Day 28

1

1

0

0

 
  

Normal Day7; Exceed Day 28

0

2

1

0

 
 

HDL-C

No Change

6

9

10

10

0.72

  

Normal Base; Exceed Day 7

2

1

0

0

 

Lipids & glucose

 

Normal Base; Exceed Day 28

1

0

1

1

 
 

Normal Day7; Exceed Day 28

2

1

2

2

 

LDL-C

No Change

9

10

13

12

0.30

 

Normal Base; Exceed Day 7

0

0

0

0

 
 

Normal Base; Exceed Day 28

2

1

0

0

 
 

Normal Day7; Exceed Day 28

0

0

0

1

 

Triglycerides

No Change

11

11

13

13

0.31

 

Normal Base; Exceed Day7

0

0

0

0

 
 

Normal Base; Exceed Day28

0

0

0

0

 
 

Normal Day7; Exceed Day28

0

0

0

0

 
 

Glucose

No Change

10

9

11

11

0.56

  

Normal Base; Exceed Day 7

1

1

1

0

 
  

Normal Base; Exceed Day 28

0

1

0

0

 
  

Normal Day7; Exceed Day 28

0

0

1

2

 
 

LDH

No Change

9

9

12

11

0.26

  

Normal Base; Exceed Day 7

1

0

0

0

 
  

Normal Base; Exceed Day 28

0

0

0

2

 
  

Normal Day7; Exceed Day 28

1

2

1

0

 

Creatine

No Change

7

7

10

11

0.75

Kinase

Normal Base; Exceed Day 7

2

1

1

0

 
  

Normal Base; Exceed Day 28

0

0

0

0

 
  

Normal Day7, Exceed Day 28

2

3

2

2

 

Muscle

Creatinine

No Change

11

9

11

11

0.32

 

Normal Base; Exceed Day 7

0

0

0

0

 
 

Normal Base; Exceed Day 28

0

1

0

2

 
 

Normal Day7; Exceed Day 28

0

1

2

0

 

Kidney

BUN

No Change

10

8

11

12

0.37

 

Normal Base; Exceed Day 7

0

0

1

0

 
 

Normal Base; Exceed Day 28

0

2

0

0

 
  

Normal Day7; Exceed Day 28

1

1

1

1

 
 

ALP

No Change

11

11

13

13

0.32

  

Normal Base; Exceed Day 7

0

0

0

0

 
  

Normal Base; Exceed Day 28

0

0

0

0

 
  

Normal Day7; Exceed Day 28

0

0

0

0

 

Liver

ALT

No Change

11

9

12

11

0.49

 

Normal Base; Exceed Day 7

0

0

0

0

 
 

Normal Base; Exceed Day 28

0

2

1

2

 
 

Normal Day7; Exceed Day 28

0

0

0

0

 

AST

No Change

8

8

12

8

0.54

  

Normal Base; Exceed Day 7

1

0

1

0

 
  

Normal Base; Exceed Day 28

1

1

0

2

 
  

Normal Day7; Exceed Day 28

1

2

0

3

 
  1. Data are presented as frequency. Statistical significance is detailed from chi-square analyses